Chemically it is based on a pyridine ring structure, with hydroxyl, methyl, aminomethyl, and hydroxymethyl substituents. Advanced Search. Yennawar NH(1), Conway ME, Yennawar HP, Farber GK, Hutson SM. Escherichia coli pyridoxine 5'-phosphate oxidase (PNPOx) catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP), forming pyridoxal 5'-phosphate (PLP). Pyridoxamine, also known as K-163, is one form of vitamin B6. Pyridoxine (pyridoxamine) 5′-phosphate oxidase (PPOX) is involved in the biosynthetic pathway of vitamin B6, converting pyridoxine 5′-phosphate (PNP) or pyridoxamine 5′-phosphate (PMP) into pyridoxal 5′-phosphate (PLP). Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). CopyCopied, CSID:1024, http://www.chemspider.com/Chemical-Structure.1024.html (accessed 12:54, Jan 25, 2021) Pyridoxamine 5'-phosphate oxidase (PNPO) deficiency. Pyridoxine 5′-phosphate oxidase's EC number is 1.4.3.5. pyridoxamine 5′-phosphate + H 2 O + O 2 → pyridoxal 5′-phosphate + NH 3 + H 2 O 2. pyridoxine phosphate + O 2 ⇌ H 2 O 2 + pyridoxal phosphate. [4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinyl]methyl dihydrogen phosphate, Cc1c(c(c(cn1)COP(=O)(O)O)CN)O Papers overview. 1.559g/cm3. MS Search. Pyridoxamine can also be converted easily into its active form pyridoxal phosphate. CopyCopied, ZMJGSOSNSPKHNH-UHFFFAOYSA-N Pyridoxal Phosphate is a coenzyme of many enzymatic reactions. Natural Isotopic Abundance Mass: 248.1729810000. The mutation, which segregated with the disorder in the … CopyCopied, InChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14) However, mammalian cells can interconvert it. CopyCopied, XYFGQXNREWPENX-UHFFFAOYSA-N Pyridoxal phosphate acts as a coenzyme in all transamination reactions, and in some oxylation and deamination reactions of amino acids. CopyCopied, InChI=1S/C8H13N2O5P.2H2O/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14;;/h3,11H,2,4,9H2,1H3,(H2,12,13,14);2*1H2 Pyridoxamine-5-phosphate bmse000131 - Data. This reaction serves as the terminal step in the de novo biosynthesis of PLP in E. coli and as a part of the salvage pathway of this coenzyme in both E. coli and mammalian cells. analogs & derivatives. The hydroxyl at position 3 and aminomethyl group at position 4 of its ring endow pyridoxamine with a variety of chemical properties, including the scavenging of free radical species and carbonyl species formed in sugar and lipid degradation and chelation of metal ions that catalyze Amadori reactions. Semantic Scholar uses AI to extract papers important to this topic. GTR Test ID Help Each Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. MS/MS Search. Pyridoxamine_5_phosphate synonyms. (5-Hydroxy-4,6-dime thylpyridin-3-yl)me thyl dihydrogen pho sphate. Molecular Formula: C8H13N2O5P. Pyridoxamine-5-phosphate. Products. Compound Pyridoxamine-5-phosphatewith free spectra: 51 NMR. Molecular Weight. PYRIDOXAMINE PHOSPHATE ANHYDROUS Q05R77UO7P Overview Structure Names 4: Classification 1: Identifiers 6: Relationships 1: Notes 3: Audit Info References 12: Moieties 1: Substance Class: Chemical Record UNII: Q05R77UO7P. Pyridoxamine 5'-pho sphic acid. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. Stars This entity has been manually annotated by the ChEBI Team. Density. Informations about Pyridoxamine 5'-Phosphate Oxidase Human Recombinant (ANG-rAP-1426-20ug) Mono-Isotopic Molecular Masses: C12N14: 248.056208048; 1D NMR Search. [4- … Drug & Food Interactions. Epilepsy due to PNPO mutations: genotype, environment and treatment affect presentation and outcome. Pyridoxamine 5'-phosphate is a vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine. Molecular formula and molecular weight of this vitamin are C 8 H 12 N 2 O 2 and 168.196 g/mol respectively. ... pyridoxamine phosphate . pyridoxamine 5'-phosphate(1−) ChEBI ID CHEBI:58451: ChEBI ASCII Name pyridoxamine 5'-phosphate(1-) Definition An organophosphate oxoanion that is the conjugate base of pyridoxamine 5'-phosphate… 951-83-7 - ICDDSMNGKMVVCW-UHFFFAOYSA-N - Pyridoxamine phosphate hydrochloride - Similar structures search, synonyms, formulas, resource links, and other chemical information. Pyridoxal Phosphate is a coenzyme of many enzymatic reactions. The RCSB PDB also provides a variety of tools and resources. 3-Pyridinemethanol, 4-(aminomethyl) ... View large 3D structure. (2014) identified a homozygous c.674G-A transition (c.674G-A, NM_001182.3) in exon 7 of the PNPO gene, resulting in an arg225-to-his (R225H) substitution at a conserved region in the PLP binding site. Formula and molecular weight of this vitamin are C 8 H 12 N 2 O 2 168.196... 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